3,5-Dimethylphenylboronic acid is an organoboron building block used mainly to introduce a 3,5-dimethylphenyl group into other molecules through carbon–carbon bond-forming reactions, especially Suzuki–Miyaura cross-coupling. Researchers and process developers may use it when designing or preparing pharmaceutical, agrochemical, and materials-related compounds, although its suitability depends on the target structure and reaction conditions. Its molecular formula is C8H11BO2, and its molecular weight is approximately 149.98 g/mol. It is a synthetic intermediate, not a finished drug or pesticide.
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This compound is an arylboronic acid: a benzene ring bearing a boronic acid group and two methyl substituents. The methyl groups occupy the 3 and 5 positions relative to the boronic acid attachment point, which defines the specific substitution pattern. It has one boron atom per molecule and is commonly considered as a reagent for transferring the corresponding aryl group in synthesis. The CAS Registry Number 172975-69-8 identifies this chemical substance.
The compound’s value comes from the combination of a reactive boronic acid functionality and a defined aromatic structure. In a suitable coupling reaction, the boronic acid group can participate in forming a new carbon–carbon bond with a compatible coupling partner. The two methyl groups remain part of the introduced aromatic fragment, influencing the structure of the resulting molecule. Reaction performance is not guaranteed by identity alone; the substrate, catalyst system, solvent, base, and process conditions all matter.
The best-established synthetic role for arylboronic acids is as coupling partners in Suzuki–Miyaura cross-coupling. In this reaction family, an arylboronic acid is commonly paired with an organic halide or another suitable electrophile in the presence of a palladium catalyst and a base. The process can create a carbon–carbon bond between the aryl fragment and the partner molecule. The exact conditions must be developed or selected for the specific substrates and production scale.
For 3,5-dimethylphenylboronic acid, this transformation offers a route to compounds containing a 3,5-dimethyl-substituted aromatic ring. That can be useful when a research target or intermediate calls for this particular substitution pattern. The reagent does not determine the final compound’s activity or performance by itself. Those properties depend on the complete molecular structure and require appropriate evaluation.
Substituted phenyl groups are common structural elements in medicinal chemistry, crop-protection research, and materials development. A boronic acid with a defined substitution pattern provides a practical starting point for exploring molecules that incorporate that aromatic fragment. Researchers may use it to prepare analogues, intermediates, or candidate structures for further study. Any application-specific benefit should be established through the relevant chemical and performance testing rather than assumed from the reagent’s name.
In pharmaceutical research, this compound may be selected during the synthesis of small molecules or intermediates that require a 3,5-dimethylphenyl unit. It can support analogue preparation, route exploration, or medicinal-chemistry investigations where that group is part of the planned structure. Its use as a starting material does not mean it is itself an active pharmaceutical ingredient, approved medicine, or evidence of therapeutic effect. Development teams should assess the identity and quality requirements appropriate to each project stage.
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Agrochemical researchers and fine-chemical manufacturers may consider the compound when a target intermediate calls for the same substituted aromatic fragment. Materials researchers may also evaluate it in synthesis routes for organic molecules or functional materials, where the final structure—not the boronic acid alone—determines material properties. These are potential development contexts, not assurances that the compound is suitable for every such project. Route feasibility, impurity control, and downstream specifications should be confirmed experimentally.
Purchasing decisions should be based on the specification required for the intended work, not only on the product name or CAS number. Confirm the stated assay or purity, test method, appearance description if relevant, packaging size, and availability of a batch-specific Certificate of Analysis. The molecular weight of approximately 149.98 g/mol can support stoichiometric calculations, but it does not replace an assay value when calculating reagent charge. Do not treat an example specification as a representation of a supplier’s current product grade.
| Item to verify | Why it matters | Buyer action |
|---|---|---|
| Identity and CAS number | Confirms that the quoted material matches the required substance. | Check the product name, CAS 172975-69-8, and relevant documentation. |
| Assay or purity | Impacts reaction calculations and may affect impurity control. | State the required acceptance criteria and request the applicable test method. |
| Batch documentation | Helps support incoming-material review and traceability. | Confirm which batch-specific documents are available before placing an order. |
| Packaging and quantity | Must suit sample evaluation, development, or production needs. | Request available pack sizes and discuss any special handling requirements. |
For early route screening, a buyer may prioritize access to a suitable evaluation quantity and clear identity documentation. Process development or manufacturing may require tighter, explicitly agreed specifications, repeatable supply, and a defined change-control or documentation process. Requirements vary by organization and intended use, so buyers should specify acceptance criteria rather than relying on broad terms such as “high purity.” If a project has regulatory or customer-specific requirements, communicate them before quotation.
Ask how the supplier identifies and releases each batch, what analytical information is included, and whether the proposed packaging is compatible with your receiving and storage procedures. Request the current Safety Data Sheet and follow its handling, storage, and transport guidance. Lead time, minimum order quantity, and shipping arrangements can vary with location, quantity, and supply status, so obtain confirmation for the specific order. Avoid assuming that a listed or quoted quantity guarantees immediate availability.
Maison Chemical supplies chemicals for B2B customers and can discuss 3,5-Dimethylphenylboronic acid, CAS 172975-69-8, in relation to a buyer’s project requirements. When requesting a quotation, include the desired quantity, target specification, destination, and any documentation needs. This information helps the supplier assess the request and clarify what can be offered. Product availability, grade, lead time, and documentation should be confirmed for each order.
For technical evaluation, provide the intended application at an appropriate level of detail and identify any critical impurity or acceptance limits. Maison Chemical can review the inquiry and communicate relevant product and supply information; buyers should independently determine whether the material and its documentation meet their internal requirements. Do not proceed on the assumption that an intermediate is suitable for a regulated or specialized application without confirming the applicable specifications. Clear requirements at the inquiry stage can reduce avoidable delays during sourcing and qualification.
3,5-Dimethylphenylboronic acid is used primarily as a synthetic building block for introducing a 3,5-dimethylphenyl group, especially through Suzuki–Miyaura coupling. It may be relevant to pharmaceutical, agrochemical, fine-chemical, and materials research when that precise aromatic fragment is needed. Whether it is the right choice depends on the target molecule, reaction route, material specification, and project stage. To move forward, define your required quantity and acceptance criteria, then ask Maison Chemical to confirm product details, documentation, and supply terms for your order.
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