2-Bromopyridine-5-carbaldehyde CAS 149806-06-4: Product Specification and Sourcing Guide

15, Sep. 2026

 

2-Bromopyridine-5-carbaldehyde CAS 149806-06-4: Product Specification and Sourcing Guide

2-Bromopyridine-5-carbaldehyde, identified by CAS 149806-06-4, is a brominated pyridine aldehyde used as a versatile intermediate in medicinal chemistry, pharmaceutical research, and advanced organic synthesis. At Maison Chemical, I help B2B buyers evaluate this compound by connecting its verified identity, project requirements, documentation needs, and supply conditions before quotation. The molecular formula is commonly represented as C6H4BrNO, with a calculated molecular weight of approximately 186.01 g/mol. Because commercial specifications can differ by production route, packaging, and quality agreement, I recommend confirming every critical parameter against the supplier’s current specification and lot documentation.

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Who This Guide Is For

I prepared this guide for procurement teams, process chemists, medicinal chemistry groups, pharmaceutical intermediate buyers, and distributors evaluating 2-Bromopyridine-5-carbaldehyde for laboratory or manufacturing use. It is also relevant to organizations that need a dependable source before moving from milligram-scale screening to gram- or kilogram-scale purchasing. The guide focuses on practical supplier communication rather than treating a general catalog description as a complete quality specification.

Basic Product Context

2-Bromopyridine-5-carbaldehyde contains two important functional features: a bromine substituent on a pyridine ring and an aldehyde group. The aldehyde can participate in transformations such as condensation and reductive amination, while the aryl bromide may provide a handle for further cross-coupling or other substitution chemistry, depending on the selected reaction conditions. These functions make the compound useful for building structurally diverse heteroaromatic intermediates.

The CAS number 149806-06-4 is an essential identity reference, but it should not be the only control used during purchasing. I advise buyers to compare the CAS number with the chemical name, molecular formula, molecular weight, structural representation, and supplier-specific product code. If the material will enter a regulated or tightly controlled process, identity confirmation and lot-specific analytical documentation should be reviewed before release.

Product Specification Overview

A useful specification should distinguish between fixed identity information and variable release criteria. Identity data generally includes the product name, CAS number, molecular formula, molecular weight, and appearance description. Release criteria may include assay, water content, residual solvents, related substances, residue on ignition, and analytical identification, but the acceptable limits must be agreed between buyer and supplier rather than assumed from a generic product page.

Specification Area What the Buyer Should Confirm
Identity CAS 149806-06-4, chemical name, formula C6H4BrNO, and approximate molecular weight of 186.01 g/mol
Appearance Supplier’s current description, physical form, and any storage-related observations
Assay and purity Test method, acceptance limit, chromatographic basis, and lot-specific result
Impurity profile Related substances, residual solvents, and process-specific impurities where relevant
Documentation Certificate of analysis, safety data sheet, batch information, and agreed quality documents
Packaging Container type, net quantity, labeling, protection from light or moisture where applicable

Why Lot-Specific Data Matters

A catalog specification describes the intended product, while a certificate of analysis describes a particular batch. I recommend requesting the latest available COA or a representative quality document during technical evaluation, then confirming that the final shipment will include batch-specific results. This approach helps buyers compare suppliers on measurable evidence instead of relying only on a nominal purity statement.

Application Matching

For medicinal chemistry, this intermediate may be selected when a project requires a brominated pyridine scaffold with an aldehyde functionality available for downstream elaboration. In route development, the buyer should evaluate not only chemical suitability but also how the material behaves in the planned reaction sequence. A small-scale compatibility experiment can help confirm whether the supplier’s material is suitable for the intended solvent, catalyst, base, temperature, and work-up conditions.

For pharmaceutical intermediate development, documentation and repeatability become increasingly important as the process moves toward scale-up. Buyers may need controlled impurity information, consistent packaging, traceability, and a defined change-notification process. For research distribution, flexibility in pack size and a clear lead-time estimate may be more important than a highly customized quality agreement.

Types, Grades, and Material Options

In practice, buyers may encounter research-grade, standard commercial, or project-specific material presentations. These labels are not interchangeable with a universally defined regulatory grade, so I advise asking what each designation means in measurable terms. The relevant questions include the assay method, analytical acceptance criteria, packaging configuration, availability of a COA, and whether the material is produced as a standard item or made against a specific order.

Some projects require only identity and purity confirmation, while others require a broader analytical package. Depending on the application, a buyer may request chromatographic data, spectroscopic support, water or residual-solvent information, and a defined retest or storage statement. Maison Chemical can discuss the appropriate document package according to the application, destination market, and purchasing stage.

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How I Recommend Selecting a Supplier

Step 1: Define the Technical Requirement

I first ask buyers to define the intended use, target quantity, required delivery region, and minimum documentation. The request should state whether the material is for route scouting, process development, analytical work, or commercial intermediate production. It should also identify any restrictions on solvents, impurities, packaging, or shipping classification.

Step 2: Compare Identity and Quality Evidence

Next, I recommend checking whether each quotation refers to the same CAS number and structure. Buyers should compare the stated formula and molecular weight, then review the proposed assay method and available analytical records. If a supplier cannot clearly explain the test basis or provide a representative COA, the buyer should treat the quotation as incomplete rather than comparing price alone.

Step 3: Confirm Commercial Conditions

Commercial evaluation should cover requested quantity, available pack sizes, MOQ, production or preparation lead time, payment terms, Incoterms, packaging, and destination requirements. MOQ and lead time are not universal properties of CAS 149806-06-4; they depend on stock status, order size, production scheduling, and export arrangements. I therefore provide these details through a project-specific quotation instead of publishing unsupported fixed promises.

Step 4: Align Documentation Before Ordering

Before purchase order approval, I suggest agreeing on the required documents and release process. This may include a COA, SDS, packing information, batch or lot identification, and any additional analytical records defined in the buyer’s quality procedure. Early alignment reduces the risk of receiving material that is chemically suitable but administratively difficult to release.

Pricing, MOQ, and Lead-Time Considerations

The final price for 2-Bromopyridine-5-carbaldehyde normally reflects quantity, availability, packaging, analytical requirements, destination, and shipping conditions. Small research quantities may have a higher unit cost because packaging and handling represent a larger proportion of the order. Larger requirements may require production planning, so buyers should provide an estimated annual demand or phased delivery schedule when possible.

I recommend requesting a quotation with at least four commercial data points: required quantity, target delivery date, destination country, and documentation expectations. For urgent projects, the buyer should ask whether the quoted material is available from existing stock or requires preparation. A clear distinction between stock supply and scheduled production gives the purchasing team a more realistic view of delivery risk.

Common Sourcing Mistakes

  • Comparing only the unit price: A lower price may exclude analytical documents, special packaging, or delivery-related costs.
  • Assuming purity standards are identical: Different suppliers may use different methods, limits, and reporting conventions.
  • Ignoring scale-up requirements: A sample suitable for screening may not provide the documentation or consistency required for process development.
  • Requesting too little information: A quotation without quantity, destination, and document requirements may not be commercially actionable.
  • Failing to confirm storage and handling: The buyer should follow the supplier’s SDS and product-specific handling guidance.

Supplier Evaluation Checklist

When I evaluate a potential supply source, I look for transparent product identification, a documented quality approach, responsive technical communication, and a practical export process. I also check whether the supplier can explain its available pack sizes, expected lead time, packaging method, and document availability without making absolute claims that cannot be verified. This evaluation is especially important when the material will be used repeatedly across multiple development batches.

Maison Chemical supports B2B inquiries for 2-Bromopyridine-5-carbaldehyde CAS 149806-06-4 by reviewing the buyer’s specifications and preparing a quotation around the actual project requirement. Our support can include product identification confirmation, commercial coordination, documentation discussion, packaging review, and shipment planning. The exact service scope depends on quantity, destination, and the buyer’s quality and regulatory expectations.

Key Takeaways

  • 2-Bromopyridine-5-carbaldehyde CAS 149806-06-4 is a brominated heteroaromatic aldehyde used as a synthetic intermediate.
  • Its commonly represented formula is C6H4BrNO, with an approximate molecular weight of 186.01 g/mol.
  • Buyers should verify identity, assay method, impurity profile, packaging, documentation, and lot-specific results.
  • MOQ, price, and lead time must be confirmed for the actual quantity, destination, and delivery schedule.
  • A complete supplier comparison should consider technical evidence and service capability, not price alone.

Conclusion and Next Steps

The best way to source 2-Bromopyridine-5-carbaldehyde CAS 149806-06-4 is to combine chemical identity verification with a project-specific commercial and documentation review. I recommend preparing a concise RFQ that includes the required quantity, application stage, target delivery date, destination, acceptable specification, and required quality documents. This gives suppliers enough information to provide a meaningful quotation and helps buyers compare offers on an equivalent basis.

As a chemicals manufacturer, supplier, and exporter, Maison Chemical can review your requirement for this pharmaceutical intermediate and discuss a suitable supply route. Please send your target quantity, specification expectations, destination, and preferred delivery schedule for evaluation. We will then confirm availability, commercial conditions, documentation options, and the next practical step for your procurement process.

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