2-(thiophen-2-yl)phenol, CAS 106584-13-8, is an aromatic phenolic compound containing a thiophene ring connected to a phenol ring. Its commonly used molecular formula is C10H8OS, with a calculated molecular weight of approximately 176.23 g/mol. The molecule combines a phenolic hydroxyl group, an oxygen-containing functional site, and a sulfur-containing five-membered heteroaromatic ring, making it a useful research intermediate for organic and medicinal chemistry investigations.
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At Maison Chemical, we position this material for professional laboratory, process-development, and research applications rather than unsupported end-use claims. Buyers should confirm the required purity, analytical documentation, packaging, and regulatory conditions before placing an order. Because physical and analytical specifications can vary by production batch, the current certificate of analysis should be used as the controlling quality document.
2-(thiophen-2-yl)phenol contains two chemically distinct aromatic systems: a phenyl ring bearing a hydroxyl group and a thiophen-2-yl substituent. The phenolic group can participate in hydrogen bonding and may influence solubility, reactivity, and downstream derivatization. The thiophene portion contributes sulfur-containing heteroaromatic character, which is relevant when researchers design compounds with extended aromatic or conjugated structures.
| Property | Commonly referenced information |
|---|---|
| Product name | 2-(thiophen-2-yl)phenol |
| CAS Number | 106584-13-8 |
| Molecular formula | C10H8OS |
| Calculated molecular weight | Approximately 176.23 g/mol |
| Structural class | Phenolic aromatic heterocycle |
The molecular formula and calculated molecular weight are useful for stoichiometric planning, literature comparison, and analytical method development. They should not be confused with a complete release specification, because identity alone does not establish purity, residual solvent content, water content, or the presence of trace by-products. For procurement, we recommend matching the product name and CAS number with the supplier’s current technical documents.
The hydroxyl group is the most apparent polar functional group in the molecule. It may affect hydrogen-bonding behavior and can serve as a site for chemical transformation, including protection, etherification, or other derivatization routes selected by the researcher. The actual reaction performance depends on the reaction system, reagent selection, temperature, concentration, and purification method.
The thiophene ring provides a sulfur-containing heteroaromatic unit that can be incorporated into exploratory compound libraries and functional molecular designs. Its presence may be relevant to studies involving aromatic stacking, electronic structure, or conjugated scaffolds. These are structural considerations, not guarantees of biological activity, conductivity, photochemical performance, or suitability for a particular product.
2-(thiophen-2-yl)phenol is primarily relevant as a research chemical and synthetic building block. Researchers may evaluate it during the preparation of substituted phenols, thiophene-containing intermediates, and small-molecule libraries. It can also be used as a starting material in route scouting when a project requires both a phenolic handle and a heteroaromatic fragment.
These applications should be treated as research categories rather than confirmed commercial performance claims. A buyer should define the intended transformation or analytical objective first, then determine whether the available grade and documentation are suitable. We do not recommend using the material in humans, animals, food, or medical products unless the complete legal, toxicological, and quality requirements for that application have been independently satisfied.
A suitable specification package should identify the material clearly and provide enough information for laboratory release and internal procurement review. At minimum, buyers commonly request the CAS number, molecular formula, molecular weight, appearance, assay or purity method, batch number, manufacturing date, and retest or recommended review date where applicable. The exact acceptance limits should be agreed before purchase rather than assumed from a product name.
| Specification area | What to confirm |
|---|---|
| Identity | CAS 106584-13-8, product name, formula, and supporting analytical data |
| Purity | Assay method, reported result, and customer acceptance limit |
| Physical description | Recorded appearance and any stated form, such as solid or powder |
| Impurity profile | Related substances, residual solvents, water, and inorganic residues when required |
| Documentation | Certificate of analysis, safety data sheet, packing information, and batch traceability |
For development work, a purity target of 95% or higher may be considered by some laboratories, while more demanding synthesis or regulated workflows may require a different limit. We do not present one universal purity value because the correct requirement depends on the application and analytical method. Buyers should also specify whether they need NMR, mass spectrometry, chromatographic data, or additional testing before quotation.
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As an aromatic organic research chemical, 2-(thiophen-2-yl)phenol should be handled according to the current safety data sheet and the controls used for laboratory chemicals. Personnel should assess exposure routes, ventilation, appropriate gloves, eye protection, spill response, and waste disposal before opening the package. A product’s structural description does not replace a substance-specific hazard assessment.
Storage conditions should be based on the supplier’s current SDS and packaging recommendation. In general procurement practice, buyers usually protect chemical solids from incompatible materials, excessive heat, moisture, and unnecessary light exposure when stability information is limited. Containers should remain tightly closed, clearly labeled, and accessible only to trained personnel.
Early route screening may require a practical research grade with reliable identity and consistent analytical data. Process development typically requires tighter control of impurities, residual solvents, packaging, and batch-to-batch comparability. If the material will support a regulated submission, the buyer should communicate those requirements before production rather than attempting to upgrade incomplete documentation afterward.
Quantity should reflect actual experimental demand, stability expectations, and the time required for qualification. A small laboratory package may reduce initial inventory risk, while a larger package can simplify repeat procurement when the specification has already been approved. We recommend confirming net weight, inner and outer packaging, labeling, shipping conditions, and expected lead time in writing.
A dependable supplier should be able to explain the available specification, provide batch-related documentation, and identify what is standard versus custom. At Maison Chemical, we support buyer discussions around product identity, required documentation, packaging options, and export coordination. Any custom testing, special packing, or forecast-based supply arrangement should be confirmed in the quotation and order documents.
Maison Chemical supplies 2-(thiophen-2-yl)phenol CAS 106584-13-8 for professional research and synthesis requirements. We focus on clear product identification, practical communication, and coordination between technical specifications and commercial delivery needs. Our role is to help buyers assess whether the available material matches their intended use, not to replace their internal quality or regulatory review.
For repeat projects, we can discuss target quantity, preferred packaging, analytical documentation, and delivery destination before preparing a quotation. This approach helps reduce avoidable differences between the requested material and the material needed by the laboratory. Where a project has special requirements, buyers should state them at the inquiry stage so feasibility can be assessed accurately.
2-(thiophen-2-yl)phenol CAS 106584-13-8 is a reasonable candidate when a project requires a phenolic aromatic structure combined with a thiophene unit. Its identity and formula support stoichiometric planning, while its two functional structural features provide opportunities for exploratory organic synthesis. However, suitability cannot be determined from the name alone.
The next step is to define your intended application, required purity, quantity, testing package, and delivery schedule. Send these requirements to Maison Chemical for a product and supply review, and we can help confirm the available specification, documentation, packaging, and quotation basis before you proceed with procurement.
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