Who This Guide Is For

I prepared this guide for pharmaceutical and agrochemical manufacturers, contract research organizations, process development teams, academic laboratories, and chemical distributors sourcing 4-Butylphenylboronic acid in research or production quantities. It is also relevant to purchasing managers who need to compare technical specifications and supplier support before requesting a quotation. The most suitable buying decision depends on the intended reaction, required scale, quality standard, and import or handling requirements in the destination market.

This article focuses on practical procurement questions: what the compound is, where it is used, which specifications deserve attention, how to compare quotations, and how to reduce avoidable sourcing risk. I use conservative language where batch-specific information must be verified through a current specification sheet or certificate of analysis.

Basic Concept and Chemical Context

4-Butylphenylboronic acid is an organoboron compound containing a boronic acid group attached to a substituted phenyl ring. The butyl group is positioned at the para, or 4-, position relative to the boronic acid functionality. The commonly listed molecular formula is C₁₀H₁₅BO₂, with a calculated molecular weight of approximately 178.04 g/mol.

The boronic acid group is valuable because it can participate in carbon–carbon bond-forming reactions with aryl or heteroaryl halides under suitable catalytic and basic conditions. In a Suzuki–Miyaura coupling, the boronic acid component transfers its organic group to the reaction partner, while the boron-containing portion is removed during the reaction process. Actual conversion depends on the substrate, catalyst, base, solvent, temperature, concentration, and work-up conditions.

Identity Information to Confirm

The molecular information above supports order identification, but it does not replace batch-release documentation. I recommend checking that the supplier’s product name, CAS number, formula, molecular weight, and analytical results are consistent across the quotation, label, specification sheet, and COA. If the project is sensitive to positional isomers or related impurities, request an analytical method or chromatographic profile suitable for your quality requirements.

Material Options and Key Specifications

For this product, “material options” generally refer to grade, purity range, package size, and documentation level rather than different basic chemical identities. A laboratory or screening project may accept a research-grade batch with standard identity data, while a regulated development program may require tighter impurity control, traceability, and change-notification procedures. I advise buyers to define these requirements before comparing suppliers.

Specifications That Matter in Procurement

• Assay or purity: Confirm the stated method, reporting basis, and acceptance limit. A purity value such as 98% should be treated as a specification claim only when it appears on the supplier’s current product documentation or batch COA.
• Identity: Request suitable evidence such as NMR, mass spectrometry, infrared analysis, or chromatographic retention data, according to your internal procedure.
• Water content: This can be important because boronic acids may interact with moisture and because water can affect some coupling conditions. Ask whether water is measured by Karl Fischer titration or another defined method.
• Residual solvents: If the material will enter a controlled process, confirm which solvents are tested and the applicable limits.
• Related substances: Ask whether the method can distinguish positional isomers, deboronated material, oxidation products, or other organic impurities relevant to your route.
• Physical description: Confirm the expected appearance and storage instructions on the product specification sheet. Do not assume that color or physical form alone proves identity.
• Packaging: Match the package to consumption rate, moisture sensitivity, transport conditions, and safe handling procedures.

Some buyers request a purity target of 98% or higher for research use, but the correct acceptance criterion depends on the reaction and downstream purification strategy. I can help customers review the available specification and determine whether the proposed grade is appropriate for screening, route development, or repeat manufacturing. Any final acceptance limit should be agreed before purchase and verified against the supplied batch documentation.

Application Matching

The primary application is use as a synthetic building block in cross-coupling chemistry. It can be considered when a process requires installation of a 4-butylphenyl substituent into an aromatic, heteroaromatic, or related molecular framework. Potential users include medicinal chemistry teams preparing analogues, process chemists developing scalable routes, and research groups studying functional organic materials.

Common Use Scenarios

• Medicinal chemistry: Introduction of a hydrophobic aryl group during analogue synthesis, subject to the specific biological target and route design.
• Agrochemical research: Preparation of substituted aromatic intermediates for discovery and process-development programs.
• Custom synthesis: Use as a coupling reagent or intermediate when a customer’s route calls for a para-butylphenyl fragment.
• Method development: Evaluation of catalyst, base, solvent, and reaction conditions for aryl–aryl bond formation.

I would not select this compound solely because it is a boronic acid. The correct choice must be checked against the electrophilic coupling partner, steric environment, electronic effects, catalyst system, and required product profile. A small-scale reaction assessment is prudent before committing to a large quantity, particularly when the route has narrow impurity limits or limited purification options.

A Practical Selection Framework

Step 1: Define the Intended Use

Start by stating whether the material is for analytical research, reaction screening, kilo-lab development, commercial manufacturing, or distribution. This determines the level of documentation, packaging, traceability, and regulatory review required. I also recommend recording the expected annual demand and the first delivery quantity, such as 10 g, 100 g, 1 kg, or another project-specific amount.

Step 2: Compare Technical Documentation

Request a current specification sheet and representative or batch-specific COA before placing the order. Review assay, identity, water, residual solvents, related substances, appearance, storage conditions, and retest or shelf-life information where available. If your quality system requires it, also ask about SDS availability, lot traceability, change-control communication, and documentation language.

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Step 3: Review Commercial Terms

Compare price together with minimum order quantity, packaging, production status, lead time, freight terms, export documents, and payment conditions. A lower unit price may not be advantageous if it requires an excessive MOQ or creates long-term storage exposure. I recommend asking whether the quoted material is in stock, made to order, or subject to a new production campaign.

Step 4: Confirm Logistics and Handling

Before shipment, confirm the package label, outer packaging, transport route, storage recommendation, and required customs information. The buyer should review the SDS and apply its own laboratory or plant safety procedures. Where the material is intended for a regulated or audited process, agree on document approval before dispatch rather than after arrival.

Pricing, MOQ, and Lead-Time Considerations

Pricing for 4-Butylphenylboronic acid can vary with purity, analytical requirements, quantity, packaging, production status, and destination. Because these factors change by project and market, I do not recommend relying on a generic online price as a final budget figure. A formal quotation should identify the exact grade, quantity, currency, Incoterm, validity period, and whether testing or special packaging is included.

MOQ is often negotiable for qualified business inquiries, but the available option depends on inventory and manufacturing planning. Small quantities may be suitable for initial screening, while larger orders may require a production schedule and pre-shipment quality review. Lead time should therefore be confirmed in writing, with separate clarity on manufacturing time, testing time, and transportation time.

Supplier Evaluation Checklist

When I assess a supplier, I look for consistent chemical identification, transparent documentation, responsive technical communication, and realistic delivery commitments. I also check whether the supplier can support repeat batches instead of treating every order as an isolated transaction. For international purchasing, export experience and document accuracy are equally important because errors can delay customs clearance or internal receiving.

1. Does the quotation clearly state 4-Butylphenylboronic acid and CAS 145240-28-4?
2. Can the supplier provide a specification sheet and COA for the offered batch?
3. Are assay, identity, water, residual solvent, and related-substance methods defined?
4. Can the supplier support the required quantity, package size, and delivery schedule?
5. Are SDS, packing information, invoices, and export documents available when required?
6. Can the supplier discuss a nonconformance process and replacement or investigation procedure?

How Maison Chemical Supports Buyers

At Maison Chemical, I position our support around practical B2B sourcing needs for 4-Butylphenylboronic acid CAS 145240-28-4. We can discuss the intended application, requested quantity, specification expectations, packaging, and destination before preparing a quotation. Where documentation is needed, we work to align the supplied product information and batch records with the buyer’s review process.

Our role is not to promise that one grade will suit every synthesis. Instead, we help buyers identify the information that must be confirmed, coordinate technical questions, and clarify commercial and logistics conditions. For repeat projects, early communication about forecast demand and acceptance criteria can make supply planning more predictable.

Common Buying Mistakes and Optimization Advice

A common mistake is ordering by product name alone without confirming the CAS number and isomer definition. Another is treating a catalog purity figure as a substitute for a batch COA, especially when the downstream process is sensitive to water or trace impurities. Buyers may also overlook the difference between quoted lead time and actual door-to-door transit time.

I recommend requesting a pre-order document pack, defining acceptance criteria, and conducting a small reaction check before scaling. Keep the original label, COA, SDS, and receiving records together with the internal lot number. If the compound is used repeatedly, establish a reorder point based on actual consumption and supplier lead time rather than waiting until the current stock is nearly exhausted.

Summary Insight

• 4-Butylphenylboronic acid CAS 145240-28-4 is an aryl boronic acid building block used primarily in coupling-based organic synthesis.
• The commonly listed formula is C₁₀H₁₅BO₂, with an approximate molecular weight of 178.04 g/mol.
• Buyers should verify assay, identity, water, residual solvents, related substances, packaging, and batch documentation.
• Price, MOQ, and lead time should be evaluated together with technical and logistics requirements.
• A clear specification review and small-scale process assessment can reduce avoidable sourcing risk.

Conclusion and Next Steps

In direct answer to the buying question, the best way to source 4-Butylphenylboronic acid CAS 145240-28-4 is to match the grade and documentation to your synthetic purpose, then compare qualified suppliers on quality evidence, quantity, delivery, and service. The compound is a useful 4-butylphenyl building block, but its suitability must be confirmed against the specific coupling route and downstream requirements. A low price without clear batch information is not a complete procurement solution.

For your next step, prepare the required quantity, target specification, package preference, destination, and desired delivery date. Send these details to Maison Chemical for a project-specific quotation and documentation review. We can then clarify available grade, MOQ, lead time, packaging, and the information needed for your internal approval before shipment.